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materialsArticleCan Differently Stabilized Silver Nanoparticles Modify Calcium Phosphate Precipitation??c c Suzana Inkret 1 , Marija Curlin two , Kristina Smokrovi?3 , Nikolina Kal ec 4 , Nikolina Perani?four , c Nadica Maltar-Strme ki 3 , Darija Domazet Jurasin 1 and Maja Dutour Sikiri?1, * c c2*?Laboratory for Biocolloids and Surface Chemistry, Division of Physical Chemistry, Ruder Boskovi?Institute, c Bijeni ka c. 54, 10000 Zagreb, Croatia c School of Medicine, Catholic University of Croatia, 10000 Zagreb, Croatia ?Laboratory for Electron Spin Spectroscopy, Division of Physical Chemistry, Ruder Boskovi?Institute, c Bijeni ka c. 54, 10000 Zagreb, Croatia c Institute for Medical Study and Occupational Health, Ksaverska cesta two, 10000 Zagreb, Croatia Correspondence: [email protected]; Tel.: + 385-1-456-?Citation: Inkret, S.; Curlin, M.; Smokrovi?, K.; Kal ec, N.; Perani?, N.; c c c Maltar-Strme ki, N.; Domazet c Jurasin, D.; Dutour Sikiri?, M. Can c Differently Stabilized Silver Nanoparticles Modify Calcium Phosphate Precipitation? Supplies 2023, 16, 1764. doi.org/ ten.3390/ma16051764 Academic Editor: Nikolaos Bouropoulos Received: 24 January 2023 Revised: 17 February 2023 Accepted: 19 February 2023 Published: 21 FebruaryAbstract: Calcium phosphates (CaPs) composites with silver nanoparticles (AgNPs) attract attention as a probable alternative to traditional approaches to combating orthopedic implant-associated infections. Even though precipitation of calcium phosphates at space temperatures was pointed out as an advantageous strategy for the preparation of a variety of CaP-based biomaterials, for the very best of our understanding, no such study exists for the preparation of CaPs/AgNP composites. Motivated by this lack of data in this study we investigated the influence of AgNPs stabilized with citrate (cit-AgNPs), poly(vinylpyrrolidone) (PVP-AgNPs), and sodium bis(2-ethylhexyl) sulfosuccinate (AOT-AgNPs) inside the concentration variety 5?five mg dm-3 on the precipitation of CaPs. The initial strong phase to precipitate inside the investigated precipitation system was amorphous calcium phosphate (ACP). The effect of AgNPs on ACP stability was significant only inside the presence of the highest concentration of AOT-AgNPs. Even so, in all precipitation systems containing AgNPs, the morphology of ACP was impacted, as gel-like precipitates formed in addition to the standard chain-like aggregates of spherical particles.Triphenylbismuth site The precise impact depended around the sort of AgNPs.m-PEG7-CH2CH2COOH Formula Right after 60 min of reaction time, a mixture of calcium-deficient hydroxyapatite (CaDHA) in addition to a smaller amount of octacalcium phosphate (OCP) formed.PMID:24633055 PXRD and EPR data point out that the amount of formed OCP decreases with increasing AgNPs concentration. The obtained outcomes showed that AgNPs can modify the precipitation of CaPs and that CaPs properties is usually fine-tuned by the option of stabilizing agent. Additionally, it was shown that precipitation could be used as a uncomplicated and fast method for CaP/AgNPs composites preparation that is of special interest for biomaterials preparation. Keywords and phrases: calcium phosphates; silver nanoparticles; amorphous calcium phosphate; transformation; composites1. Introduction Calc.
